What is 
Endura-KT™ is a sterile, preservative-free compounded local anesthetic preparation containing tetracaine 0.2%, lidocaine 0.4% and epinephrine 1:250,000 after preparation. It is designed to support clinicians in managing procedural and post-operative discomfort.
Developed by clinicians who identified a need for an additional approach to local anesthetic management, Endura-KT gives licensed healthcare professionals an opioid-free local anesthetic option to consider when they determine that a compounded preparation is appropriate for a patient and procedure.
Healthcare Professionals
Explore product, clinical, safety, and handling information.
Patients & Caregivers
Understand Endura-KT, compounded medications, and what to discuss with your provider
Endura-KT is a compounded drug preparation and is not FDA approved. FDA does not review compounded drugs for safety, effectiveness or quality before marketing.
Why was Developed?
The story behind Endura-KT
The Difference
A New procedural approach to post-procedural pain
Opioid-free formulation containing tetracaine, lidocaine and epinephrine
Sterile and preservative-free preparation
Balanced, dilute concentrations intended to permit adequate volume administration at the procedural site
Multiple vial sizes to support different anticipated procedural volumes and established clinical workflows
Broad dental applicability, including clinician-directed use in extractions, implant placement, periodontal and endodontic surgery, grafting and related interventions
For patients, Endura-KT provides a local anesthetic option without systemic opioid administration. For practices, its standardized formulation, multiple vial sizes and office-stock availability where permitted may support procedure planning and workflow efficiency. Individual response, duration of effect and clinical outcomes vary, and the treating clinician determines whether Endura-KT is appropriate.
Our goal is to provide clinicians with clear, responsible, and compliant educational information that supports understanding of this compounded option, including its components, handling, and potential procedural applications as determined by the healthcare provider.
in Dentistry
Supporting Dental Professionals with Advanced Compounded Solutions
Ventis Pharma’s Dental Division is dedicated to supporting dental professionals with high-quality compounded preparations produced under a cGMP environment regulated by the Federal Food, Drug, and Cosmetic Act. We focus on developing innovative solutions that address the evolving needs of oral and maxillofacial surgeons, periodontists, endodontists, and general dentists while maintaining a commitment to quality, consistency, and patient-centered care.
Learn How Endura-KT Can Fit Into Your Practice
Discover how dental professionals are incorporating Endura-KT into their procedural anesthesia and post-procedural patient management protocols. Connect with our team to discuss clinical applications, ordering information, and educational resources.
The Standards Behind
Endura-KT™ a Patented Formulation is a Compounded Preparation manufactured by a cGMP facility that is inspected by the FDA, State Board of Pharmacy and the DEA
Manufactured with Defined Quality Controls
Endura-KT is compounded by OurPharma, subject to current Good Manufacturing Practice requirements and risk-based FDA inspection. OurPharma’s quality systems include environmental monitoring, vendor qualification, visual inspection, third-party release testing and documented lot-release review.
Clinical / Professional Applications
Where Endura-KT may fit
Dentistry
Clinicians have reported utilizing Endura-KT in a variety of dental and oral healthcare procedures, including oral surgery, periodontics, endodontics, implant dentistry, and complex restorative treatments. Reported uses range from extractions and bone grafting to root canal therapy, periodontal surgery, implant procedures, and full-mouth rehabilitation. Treatment decisions are made by the healthcare provider based on individual patient and procedural considerations.
Hospital Surgery / Perioperative Teams
Endura-KT is a sterile cGMP-compounded anesthetic preparation that may be incorporated into perioperative workflows at the clinician’s discretion. Surgical teams may consider compounded anesthetic preparations in cases where FDA-approved alternatives do not meet patient-specific or procedural requirements.
Anesthesia
Endura-KT is a cGMP-compounded combination of tetracaine, lidocaine, and epinephrine formulated for use by licensed anesthesia providers. It may be chosen when a clinician determines that a compounded anesthetic preparation aligns with a particular block technique, workflow, or patient presentation.
Emergency Medicine & Trauma
Emergency clinicians may use Endura-KT—a cGMP-compounded anesthetic formulation—when they determine that a compounded preparation supports their approach to procedural analgesia, laceration management, or other emergent interventions requiring localized anesthesia.
Ambulatory Surgery Centers (ASC)
Endura-KT is a sterile cGMP-compounded anesthetic option that ASC providers may select when they determine that a ready-to-use compounded formulation supports their procedural environment, workflow efficiency, or individualized patient needs.
Surgical Oncology
Oncology surgical teams may choose Endura-KT, a cGMP-compounded anesthetic preparation, when a clinician determines that a tailored anesthetic formulation supports the requirements of tumor-related or complex surgical interventions.
OB-GYN Surgery
OB-GYN providers may incorporate Endura-KT, when appropriate, as a cGMP-compounded anesthetic preparation in procedures requiring localized or adjunctive anesthesia, based on clinician judgement regarding patient needs and procedural goals.
Plastic & Reconstructive Surgery
Licensed plastic surgeons may use Endura-KT—a cGMP-compounded tetracaine/lidocaine/epinephrine formulation—when determining their anesthetic approach for reconstructive or aesthetic procedures requiring localized anesthesia.
Wound Care / Limb Salvage / Chronic Ulcer Procedures
Wound care specialists may elect to use Endura-KT as a cGMP-compounded anesthetic preparation when localized anesthesia is needed for debridement or procedural interventions and when clinicians determine that a compounded option supports patient-specific needs.
Podiatry
Podiatric surgeons may consider Endura-KT, a cGMP-compounded anesthetic preparation, when determining localized anesthesia strategies for foot and ankle procedures based on patient-specific or procedural-specific needs.
Proctology / Colorectal Surgery
Colorectal and proctologic surgeons may incorporate Endura-KT—when deemed appropriate by the clinician—as a cGMP-compounded anesthetic preparation to support localized anesthesia for office-based or surgical interventions.
Learn More About Endura-KT
Healthcare professionals can access current product information, request educational support or begin the account and ordering process.
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Trusted partner
Ventis Pharma is dedicated to providing healthcare professionals with high-quality compounded preparations produced under a cGMP environment regulated by the Federal Food, Drug, and Cosmetic Act.
Supporting Dental Professionals with Advanced Compounded Solutions
Our Dental Division focuses on offering products that meet the clinical needs of oral and maxillofacial practitioners seeking consistent quality and dependable performance.
Endura-KT™ is a cGMP compounded preparation and has not been evaluated or approved by the FDA. Educational content is provided solely for licensed healthcare professionals to support informed clinical decision-making.
No safety or efficacy claims are being made.
This website is designed for licensed healthcare professionals involved in perioperative care, procedural anesthesia, surgery, dentistry, emergency medicine, and other clinical specialties.